Non-profit research & innovation institute

Mbale, Uganda · Since 2020

Rigorous science, born where the need is greatest.

AMANI generates world-class evidence — and translates it into practical, affordable solutions — for the health of women, newborns, children, and adolescents across Africa and beyond.

150+
Publications
5
Active trials

Working in partnership with

  • Elgon Local Maternity and Neonatal System

    Elgon Local Maternity and Neonatal System

  • Mbale Regional Referral Hospital

    Mbale Regional Referral Hospital

  • Ministry of Health, Republic of Uganda

    Ministry of Health, Republic of Uganda

An AMANI fieldworker walking a family through study information at a community enrolment day

Mbale Regional Referral Hospital Complex
Pallisa Road, Mbale City, Uganda

Closing the gap in research from the global South

Founded in 2020 in Mbale, Uganda, AMANI generates rigorous scientific evidence — and turns it into practical, affordable solutions — for the most pressing health challenges facing women and children across Africa.

Mission

To generate and translate health knowledge into scalable, affordable solutions for maternal, newborn, child, and adolescent health in low-resource settings.

Vision

A leading African research institute producing the next generation of global health leaders — and solutions that improve outcomes across the continent.

150+
Peer-reviewed publications by our researchers
5
Active trials & cohorts across Uganda
6,000
Mother–infant pairs in the BabyGel Trial
1,242
Very low birthweight infants in the SSOSS Trial

The full spectrum, from evidence to impact

AMANI works across the entire arc of health research and innovation — from first protocol to market-ready solution.

  • Research

    Rigorous clinical trials, epidemiological studies, and health systems evaluations that generate high-quality, policy-relevant evidence.

  • Innovation

    Context-appropriate healthcare solutions for resource-limited settings, with incubation and scaling of high-potential health innovations.

  • Training & Capacity Building

    Fellowships, workshops, and embedded research training for students, junior faculty, health professionals, and community health workers.

  • Consulting & Advisory

    Expert support to governments, NGOs, and health funders on programme design, evaluation, and strategy — grounded in real-world data.

  • Laboratory Services

    Research-level laboratory support for clinical and epidemiological studies in eastern Uganda, aligned to international standards.

  • Knowledge & Commercialisation

    Publishing, seminars, and educational materials — plus partnering with industry and investors to scale proven innovations to market.

Trials & cohorts shaping clinical practice

Our portfolio spans neonatal survival, obstructed labour, infection prevention, and women's health — enrolling thousands of participants across Uganda.

SSOSS Trial — Neonatal healthNeonatal health

SSOSS Trial

Co-PI · Prof. David Mukunya

Assessing the effectiveness of emollient therapy in reducing mortality and infections, and promoting neurodevelopment, among 1,242 very low birthweight infants.

SoBiCOL-II Trial — Maternal healthMaternal health

SoBiCOL-II Trial

PI · Prof. Milton Musaba

Evaluating sodium bicarbonate administration in obstructed labour for reducing maternal and neonatal morbidity.

ENON Cohort Study — Cohort studyCohort study

ENON Cohort Study

PI · Prof. David Mukunya

Examining the effect of probable neonatal sepsis on infant development, blood pressure, and renal function in Eastern Uganda.

Lactate Study — Maternal sepsisMaternal sepsis

Lactate Study

Using point-of-care lactate testing to improve identification of maternal sepsis in resource-limited settings.

VITAL-HMB Study — Women's healthWomen's health

VITAL-HMB Study

PI · Prof. Milton Musaba

A Wellcome Leap–funded study validating predictive models to detect women at risk of heavy menstrual bleeding and iron deficiency.

Our work, in pictures

From the laboratory bench to school screening days across eastern Uganda — the everyday work behind the evidence.

  • Reaching hundreds of students at a school outreach day in eastern Uganda

    Reaching hundreds of students at a school outreach day in eastern Uganda

  • Inside the biobank — showing students the −80° sample freezer

    Inside the biobank — showing students the −80° sample freezer

  • Walking a family through study consent at a community enrolment day

    Walking a family through study consent at a community enrolment day

  • Enrolling a participant at the VITAL-HMB field tent

    Enrolling a participant at the VITAL-HMB field tent

  • Recording participant readings on a study tablet

    Recording participant readings on a study tablet

  • VITAL-HMB screening bays set up in a school courtyard

    VITAL-HMB screening bays set up in a school courtyard

  • Students with study information leaflets at a school session

    Students with study information leaflets at a school session

Clinicians & scientists with two decades in the field

Our leadership pairs frontline clinical experience with internationally recognised research careers.

  • Prof. Milton W. Musaba

    Executive Director & Co-Founder

    MBChB, MSc, M.Med (O&G), PhD · Consultant Obstetrician & Gynaecologist

  • Prof. David Mukunya

    Deputy ED, Head of Research & Co-Founder

    MD, PhD · Physician-scientist & epidemiologist, 150+ publications

  • Dr. Kenneth Mugabe

    Clinical Director

    Clinician & health-systems leader · National Safe Motherhood award winner

  • Dr. Josephine Tumuhamye

    Laboratory Director

    MSc, PhD · Microbiological, haematological & molecular analysis

  • Ms. Brendah Nambozo

    Chief Operations Officer

    Researcher & operations leader · Infrastructure, HR & programme management

  • Dr. Frank Kayemba

    Head of Artificial Intelligence & Health

    MBChB, Global Arts in Medicine Fellow · AI & digital health

Evidence that survives global scrutiny

Our work appears in leading international journals and directly informs national guidelines on neonatal care, infant feeding, and obstetric practice.

Research data capture underpinning AMANI's published evidence

150+

peer-reviewed publications by our researchers

Neonatal sepsis at Mulago national referral hospital in Uganda: etiology, antimicrobial resistance, associated factors and case fatality risk

Acceptability of the Moyo device for intrapartum fetal heart rate monitoring at a referral hospital in Uganda: a qualitative study

Decreased renal function among children born to women with obstructed labour in Eastern Uganda: a cohort study

Let's build the evidence that changes outcomes

Whether you are a funder, government agency, academic institution, or industry partner — join us in translating world-class African research into solutions that save lives.